Eddie Vedder is debuting a new song called “Matter Of Time” tonight at Venture Into Cures, a virtual benefit event for the EB Research Partnership, Jill and Eddie Vedder’s nonprofit dedicated to funding research aimed at treating and curing Epidermolysis Bullosa. Vedder will also play a new version of “Say Hi.”

The event will also feature musical performances from Jon Batiste, Alessia Cara, Andra Day, Glen Hansard, Adam Levine, Keb’ Mo’, Lukas, and Micah and Willie Nelson, plus appearances from Judd Apatow, Bradley Cooper, Laura Dern, Billie Eilish, Chris Hemsworth, Jimmy Kimmel, David Letterman, Gaten Matarazzo, Luis “King Kong” Ortiz, Adam Sandler, and Renée Zellweger.

Watch the livestream below starting at 8PM EST.